Jessi had colic and about the only thing that helped was carrying her around face down in the crook of my arm or laying her across my lap and patting her back while "bumping" her. Guess it relieved the pressure.
TJ had reflux and there really wasn't much I could do for him. I tried only feeding him sitting up and not laying him down immediately after eating, but he still spit up constantly. In hindsight I probably should have tried different formulas, but it was never suggested to me. I just assumed once he was eating solids, it would go away (NOT! Then they go from spitting up to throwing up!)